The TRPV3 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to TRPV3. This antibody recognizes Human, and Mouse antigen. The TRPV3 Antibody has been validated for the following applications: ELISA, and Western Blot.
Description
Function: Putative receptor-activated non-selective calcium permeant cation channel. It is activated by innocuous (warm) temperatures and shows an increased response at noxious temperatures greater than 39 degrees Celsius. Activation exhibits an outward rectification. May associate with TRPV1 and may modulate its activity. Is a negative regulator of hair growth and cycling: TRPV3-coupled signaling suppresses keratinocyte proliferation in hair follicles and induces apoptosis and premature hair follicle regression (catagen).
Subunit Structure: May form a heteromeric channel with TRPV1. Interacts with TRPV1.
Similarity: Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV3 sub-subfamily